Rabies is a fatal zoonotic disease spread worldwide. The most common sources of infection for all animals and humans are bites from dogs or bats. The aim of this degree project was to diagnose and determine the source of infection for 11 rabies samples from São Paulo State and Minas Gerais State, Brazil. Diagnosis was made through direct immunofluorescence assay, mouse inoculation and RT-PCR. The sources of infection were determined by sequencing 234 nucleotides of the 5? end of the N-gene and align these with homologous sequences retrieved from GenBank.

Although known and feared for thousands of years, rabies remains a real and present threat to thousands of people, especially in low- and middle income countries. In India, rabies is an endemic disease, causing human deaths every year. The primary mode of transmission is through the bite of an infected dog. Fighting the disease in the dog population through vaccinations remains the most efficient way to eradicate the disease. The knowledge of rabies in India is unsatisfactory, as a lot of people lack awareness about the severity of the disease and the importance of washing the bitten area and seeking medical attention for post exposure prophylaxis when bitten by a dog.

This literature study describes the ways in which the spread of rabies can be prevented in India, what guidelines are set and also which methods have proved most effective. Every year rabies causes the death of around 20 000 people in India, which makes the prevalence in the country the highest in the world. The main source for human infection is bite wounds from infected dogs. People and animals can be vaccinated both prophylactic and post-exposure prophylactic (PEP), despite this the disease continues to claim high number of victims. The majority of those dying are young men and children from the poorer part of the population. Knowledge among the Indian population on rabies and its transmission routes, wound care and vaccinations is very limited.

Dog bites pose a threat to public health globally and can lead to infection, disfigurement, incapacity, post-traumatic stress syndrome and even death. In geographical areas where rabies is endemic, bites from infected dogs account for over 90% of the human rabies cases. Children have been proven to be at a greater risk of being bitten by dogs and subsequently contracting rabies than adults. In this cross-sectional study, a school survey was undertaken in association with a rabies awareness campaign in India, to investigate the dog bite incidence and various risk factors associated with dog bites as well as assessing the knowledge of safe interaction with dogs among children in the age group 10-18 years. A total of 1295 questionnaires were collected. 43.2 % (n=556) out of the respondents were boys and 56.8 % (n=731) were girls with a mean age of 14 years.

Rabies kills about 55 000 people every year and more than 90% of infected humans are considered getting the disease from dog-bites. To control the disease and eventually eliminate human rabies, the most efficient and economic method is to keep the dog population vaccinated. The objective of this thesis was to evaluate the situation of canine rabies in two urban areas in Lilongwe, Malawi, where canine rabies is enzootic. In each area 200 household-interviews were conducted in September and October 2013. Focal points were awareness of the disease, human incidence as well as vaccination coverage in the dog population.

Rabies sprids vanligen genom ett bett av ett infekterat djur men det förekommer även andra spridningsvägar. Två av dessa är genom inandning av rabiesvirus, det vill säga aerosol spridning och via organtransplantation då donatorn är infekterad med rabies. Då det inte finns någon vedertagen behandlingsmetod för sjukdomen när symptom väl uppträtt måste sjukdomen förhindras innan detta sker. Rabies kan förhindras med vaccinering, både hos djur och människor. För att stoppa spridningen bör man fokusera på de viktigaste smittspridarna, bland annat fladdermöss och hundar.

Rabies är en virussjukdom som smittar via saliv och orsakar hjärnhinneinflammation hos drabbade individer. Om viruset inte behandlas innan symptom bryter ut leder sjukdomen ofrånkomligen till döden. Rabies orsakar stora problem världen över, men jag har valt att fokusera på Afrika där sjukdomen orsakar cirka 24 000 humana dödsfall varje år. Värst drabbade är fattiga människor på landsbygden. Man räknar med att 99 % av alla humana dödsfall beror på smitta från domesticerade hundar och att 40 % av alla drabbade är barn under 15 år.

This literature review summarizes available data on infection with the parasitic roundworm, Ascaridia galli, as a cause of disease in poultry, including the consequences of a conversion to alternative production systems. Ascaridia galli has a direct life cycle with resistant eggs that survive and are easily spread in the environment, especially in systems with bedding materials where the faecal contact is high. The infection is usually subclinical but depending on the infection dose, the symptoms range from weight loss and diarrhea to mortality. Factors such as the feed composition and genetic variation among different hybrids clearly affect the establishment rate of the infection. Ascaridia galli will probably become an increasing problem, with a shift from the traditional battery cages to alternative systems where the risk of re-infection is high.

This literature review summarizes available data on infection with the parasitic roundworm, Ascaridia galli, as a cause of disease in poultry, including the consequences of a conversion to alternative production systems. Ascaridia galli has a direct life cycle with resistant eggs that survive and are easily spread in the environment, especially in systems with bedding materials where the faecal contact is high. The infection is usually subclinical but depending on the infection dose, the symptoms range from weight loss and diarrhea to mortality. Factors such as the feed composition and genetic variation among different hybrids clearly affect the establishment rate of the infection. Ascaridia galli will probably become an increasing problem, with a shift from the traditional battery cages to alternative systems where the risk of re-infection is high.

Cross infection is a global health problem. The cost for cross infection increases every year. Florence Nightingale focused her attention on preventing cross infections by using good hygiene and as a nurse that is one of your more important tasks. Nurses have guidelines for how hygiene should be implemented in practice. The aim of this study is to investigate factors that influence nurses´ compliance to guidelines regarding hygiene.

India is the country with the highest prevalence of rabies in the world, with about 20?000 human deaths occurring every year. The country also has a heavy burden of free roaming dogs, mainly because of the high amount of edible waste in the streets, which are the main hosts for the disease. Therefore to truly extinguish rabies, the main focus should be on the dogs, both stray dogs and owned. One method is to vaccinate all dogs against rabies.

Regardless of what discipline nurses work in, wound care is one of the tasks. Caring for wounds involves early detection of signs of infection, in order to avoid complication. Wound infection extends suffering for the patient and causes unnecessary costs for society. The aim was to describe how nurses can identify infection in wounds. Method: The design of the study was a literature review, where13 scientific articles were examined and analyzed.

Regardless of what discipline nurses work in, wound care is one of the tasks. Caring for wounds involves early detection of signs of infection, in order to avoid complication. Wound infection extends suffering for the patient and causes unnecessary costs for society. The aim was to describe how nurses can identify infection in wounds. Method: The design of the study was a literature review, where13 scientific articles were examined and analyzed.

Rabies är en virussjukdom som årligen skördar många dödsoffer i framförallt utvecklingsländer i bland annat Afrika. Spridningen av sjukdomen till människor sker huvudsakligen via hundar och hundbett och flera olika strategier har tillämpats i försök att stävja smittspridning och hindra humana dödsfall. Övervakning av rabiessituationen ger verktyg att planera insatser och utveckling kring förenkling av diagnostiska metoder är under arbete. Övervakning i kombination med vaccinationskampanjer riktade mot afrikanska hundar i syfte att genom flockimmunitet i hundpopulationen hindra humana dödsfall har givit goda resultat. Det är dock viktigt att beakta att olika strategier ger varierande resultat beroende på i vilka miljöer de tillämpas samt att en tillräckligt stor andel av hundpopulationen måste immuniseras.

Postoperative site infections are the second most common health care associated infection in Sweden. Surgical procedures can lead to postoperative site infection causing great suffer for the patient and an extended care time with an increased cost as a result. In preparation for surgery, it is important that the skin is well prepared with antiseptics to decrease the risk of postoperative site infection. The purpose with this study was to shed light upon the skin preparation before surgery and its significance to postoperative site infection. Ten scientific articles have been scrutinized and compiled and two themes have been identified ? the preoperative and the intraoperative skin preparation.